"We have a policy in our family, no secrets," Pitt, 49, told Extra at an after-party for World War Z. "I mean, there's an age of understanding, so you've got to present it in a way that is age appropriate, but we know our children very well."
The film's London premiere Sunday marked Jolie's first piblic appearance since revealing she had had surgery.
"We want everything to be on the table and any questions they have, for them to ask," Pitt said of their kids, who range in age from 4 to 12.
Jolie, 37, wearing a black Saint Laurent dress, said she has been "very moved" by the support she received from people after revealing in an op-ed in The New York Times that she underwent a double mastectomy on Feb. 16 and then had reconstructive surgery on April 27.
Jolie, who turns 38 on June 4 and is set to direct Unbroken, toold the BBC she was proud to shine a light on an issue important to all women. "I've been very happy just to see the discussion about women's health expanded, and that means the world to me."
Pitt's zombie thriller World War Z opens in U.S. theaters June 21.
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